Structure of PDB 9bdl Chain AL18

Receptor sequence

>9bdlAL18 (length=187) Species: 9986 (Oryctolagus cuniculus)

GVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRL
FMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRVQEVPKLKVC
ALRVTSRARSRILKAGGKILTFDQLALDSPKGRGTVLLSGPRKGREVYRH
FGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN

3D structure

• PDB: 9bdl Structural mechanism of angiogenin activation by the ribosome.
• Chain: AL18
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AL18	G2 H7 N8 D10 R11 K12 V13 R14 R15 S20 K30 F34 R37 R38 T42 F43 K49 R50 M53 S54 R55 T56 N57 S64 R65 R68 K69 L72 P73 G74 R75 K78 T85 T87 D88 D89 V90 R91 R104 T106 S107 R108 R134 G135 T136 L138 S140 P142 R143 K144 G145 R146 E147 V148 R150 F152 T158 P159 H160 H162 K164 P165 Y166 V167 R168 R172 K173 E175 R176 R178 R180 R181 S183 R184 G185 Y186 N188	G1 H6 N7 D9 R10 K11 V12 R13 R14 S19 K29 F33 R36 R37 T41 F42 K48 R49 M52 S53 R54 T55 N56 S63 R64 R67 K68 L71 P72 G73 R74 K77 T84 T86 D87 D88 V89 R90 R103 T105 S106 R107 R133 G134 T135 L137 S139 P141 R142 K143 G144 R145 E146 V147 R149 F151 T157 P158 H159 H161 K163 P164 Y165 V166 R167 R171 K172 E174 R175 R177 R179 R180 S182 R183 G184 Y185 N187

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation

Cellular Component

• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum
• GO:0005791 rough endoplasmic reticulum
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:9bdl, PDBe:9bdl, PDBj:9bdl
• PDBsum: 9bdl
• PubMed: 38718836
• UniProt: G1TFE0|RL18_RABIT Large ribosomal subunit protein eL18 (Gene Name=RPL18)