Structure of PDB 7tor Chain AL11

Receptor sequence

>7torAL11 (length=170) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

KENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTV
RSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGF
GIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRI
SKEEAMRWFQQKYDGIILPG

3D structure

PDB

7tor Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.

Chain

AL11

Resolution

2.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	AL11	K19 C21 N23 C25 S51 A53 R54 Y55 F60 I68 R95 N97 N98 D101 T102 G106 F107 G108 G127 L128 D129 Y131 K145	K12 C14 N16 C18 S44 A46 R47 Y48 F53 I61 R88 N90 N91 D94 T95 G99 F100 G101 G120 L121 D122 Y124 K138
BS02	rna	AL11	N10 M12 R13 Q46 T47 V49 T73 R75 P137 G138 S140 I141 D143 K144 C150 I151 A153 K154	N3 M5 R6 Q39 T40 V42 T66 R68 P130 G131 S133 I134 D136 K137 C143 I144 A146 K147
BS03	rna	AL11	T56 R58 R64	T49 R51 R57

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7tor, PDBe:7tor, PDBj:7tor
PDBsum	7tor
PubMed	35589706
UniProt	G1TUB8\|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)

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