Structure of PDB 4v85 Chain AL

Receptor sequence

>4v85AL (length=123) Species: 562 (Escherichia coli) [Search protein sequence]

ATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRK
VCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGA
LDCSGVKDRKQARSKYGVKRPKA

3D structure

PDB

4v85 Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome.

Chain

Resolution

3.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	AL	A1 T2 N4 Q5 L6 R8 R11 A12 R13 S18 A25 C26 P27 Q28 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 G67 G68 E69 L80 R82 R85 K87 D88 P90 R93 R109 K110 Q111 A112 R113 S114 K115 Y116 V118 K119 R120	A1 T2 N4 Q5 L6 R8 R11 A12 R13 S18 A25 C26 P27 Q28 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 G67 G68 E69 L80 R82 R85 K87 D88 P90 R93 R109 K110 Q111 A112 R113 S114 K115 Y116 V118 K119 R120
BS02	MG	AL	P44 N45	P44 N45
BS03	MG	AL	A22 L23	A22 L23

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0034336	misfolded RNA binding

	Biological Process
GO:0000372	Group I intron splicing
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0033120	positive regulation of RNA splicing
GO:0034337	RNA folding
GO:0046677	response to antibiotic
GO:1990145	maintenance of translational fidelity

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:4v85, PDBe:4v85, PDBj:4v85
PDBsum	4v85
PubMed	22187675
UniProt	P0A7S3\|RS12_ECOLI Small ribosomal subunit protein uS12 (Gene Name=rpsL)