Structure of PDB 6hix Chain AI

Receptor sequence
>6hixAI (length=212) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
VAPWVPPPRHDIKVTMPPPPGGEVGGRFGVSQGYSDRLARTPYWKRMALS
TYKLRMMENATRYPMSEHRPGEYDIRYLPTPYPCTIRNRPLLEVGEPRQI
PSIRIPVIFLVNLFDEAKGCWFGRRYETVYVERQFMREELMPQRYAIYAT
PEAYKLLGLPVVNHHTHEEIPKTPREYEKLLERQRYDEERWKYTIEYLFR
KYEDGPPELLDR
3D structure
PDB6hix Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
ChainAI
Resolution3.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AI R35 Y90 P91 V102 P105 R106 Q142 R27 Y82 P83 V94 P97 R98 Q134
BS02 peptide AI V102 G103 V94 G95
BS03 peptide AI N120 F122 E124 F130 E147 Q151 N112 F114 E116 F122 E139 Q143
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm

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Cellular Component
External links
PDB RCSB:6hix, PDBe:6hix, PDBj:6hix
PDBsum6hix
PubMed30213880
UniProtQ57UC5

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