Structure of PDB 6tb3 Chain AH

Receptor sequence

>6tb3AH (length=121) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

KALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSET
AMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKK
AYVRLTADYDALDIANRIGYI

3D structure

PDB

6tb3 The Ccr4-Not complex monitors the translating ribosome for codon optimality.

Chain

Resolution

2.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AH	L24 R33 L34 P35 K39 R42 A43 P44 K45 Y46 S69 T71 K75 N91 K92 Y93 K109 N111 T112 L113 V114 P116 K120 K121 Y123 R125	L3 R12 L13 P14 K18 R21 A22 P23 K24 Y25 S48 T50 K54 N70 K71 Y72 K88 N90 T91 L92 V93 P95 K99 K100 Y102 R104
BS02	rna	AH	L24 R27 T37 L38 R42 S48 K49 H53 Y54 N55 R56 K61 K89 Y93 Q94	L3 R6 T16 L17 R21 S27 K28 H32 Y33 N34 R35 K40 K68 Y72 Q73

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

External links

PDB	RCSB:6tb3, PDBe:6tb3, PDBj:6tb3
PDBsum	6tb3
PubMed	32299921
UniProt	P04456\|RL25_YEAST Large ribosomal subunit protein uL23 (Gene Name=RPL25)