Structure of PDB 4v9a Chain AH

Receptor sequence
>4v9aAH (length=151) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLA
VQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGA
VPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG
E
3D structure
PDB4v9a Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
ChainAH
Resolution3.2999 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AH R14 T16 A17 R18 M19 Q20 A21 R24 R25 K47 P49 K57 Y61 F84 A86 A94 A102 L119 T120 K121 E122 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 R20 R21 K43 P45 K53 Y57 F80 A82 A90 A98 L115 T116 K117 E118 S121 R122 N123 N126 Y129
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4v9a, PDBe:4v9a, PDBj:4v9a
PDBsum4v9a
PubMed23431179
UniProtQ5SHQ5|RS5_THET8 Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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