Structure of PDB 4v6s Chain AH

Receptor sequence

>4v6sAH (length=176) Species: 562 (Escherichia coli)

SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK

3D structure

• PDB: 4v6s Structural characterization of mRNA-tRNA translocation intermediates.
• Chain: AH
• Resolution: 13.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AH	S1 R2 V3 K5 L36 D38 G56 Y57 A58 D59 W61 A62 Q63 G65 T66 A69 L70 V91 G107 F108 S109 H110 Q115 K137 Q138 G141 Q142 A145 D146 R148 A149 Y150 R152 P155 Y156 K157 K159 Y163 D165 V167 R169 T170 K171 E172 A173 K174 K175 K176	S1 R2 V3 K5 L36 D38 G56 Y57 A58 D59 W61 A62 Q63 G65 T66 A69 L70 V91 G107 F108 S109 H110 Q115 K137 Q138 G141 Q142 A145 D146 R148 A149 Y150 R152 P155 Y156 K157 K159 Y163 D165 V167 R169 T170 K171 E172 A173 K174 K175 K176

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0070180 large ribosomal subunit rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0046677 response to antibiotic

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v6s, PDBe:4v6s, PDBj:4v6s
• PDBsum: 4v6s
• PubMed: 22467828
• UniProt: P0AG55|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)