Structure of PDB 6tnu Chain AG

Receptor sequence

>6tnuAG (length=169) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

6tnu The Ccr4-Not complex monitors the translating ribosome for codon optimality.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AG	K16 N20 S22 G24 R51 Y52 F57 H68 R94 N95 S97 A98 N101 F104 G105 D107 G124 M125 Y128 R140 K142	K11 N15 S17 G19 R46 Y47 F52 H63 R89 N90 S92 A93 N96 F99 G100 D102 G119 M120 Y123 R135 K137
BS02	rna	AG	P8 M9 T44 V46 T70 R72 R137 V138 R141 R143 V148 G149 N150 H152	P3 M4 T39 V41 T65 R67 R132 V133 R136 R138 V143 G144 N145 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6tnu, PDBe:6tnu, PDBj:6tnu
PDBsum	6tnu
PubMed	32299921
UniProt	P0C0W9\|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

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