Structure of PDB 6tb3 Chain AG

Receptor sequence

>6tb3AG (length=169) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

6tb3 The Ccr4-Not complex monitors the translating ribosome for codon optimality.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	AG	T53 R55 R61	T48 R50 R56
BS02	rna	AG	K16 V18 N20 S22 S48 A50 R51 Y52 F57 I59 A66 H68 R94 N95 A98 T99 N101 G103 F104 G105 D107 G124 M125 Y128 V130 K142 K174	K11 V13 N15 S17 S43 A45 R46 Y47 F52 I54 A61 H63 R89 N90 A93 T94 N96 G98 F99 G100 D102 G119 M120 Y123 V125 K137 K169
BS03	rna	AG	P8 M9 Q43 T44 V46 T70 R72 G135 R137 R141 R143 T147 G149 N150 H152	P3 M4 Q38 T39 V41 T65 R67 G130 R132 R136 R138 T142 G144 N145 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6tb3, PDBe:6tb3, PDBj:6tb3
PDBsum	6tb3
PubMed	32299921
UniProt	Q3E757\|RL11B_YEAST Large ribosomal subunit protein uL5B (Gene Name=RPL11B)

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