Structure of PDB 7p5x Chain AF

Receptor sequence
>7p5xAF (length=318) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
EALRQARKDAELTASADSVRAYLKQIGKVALLNAEEEVELAKRIEAGLYA
TQKLAELAEKGEKLPVQQRRDMQWICRDGDRAKNHLLEANLRLVVSLAKR
YTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAM
ADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITPEK
VLEIQQYAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVSFTLLQDQ
LQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESK
TMSKLRHPSRSQVLRDYL
3D structure
PDB7p5x Transcriptional control of mycobacterial DNA damage response by sigma adaptation.
ChainAF
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna AF R167 L170 G174 L178 R239 L240 S243 D274 K277 Y279 K280 S282 Y284 W287 Q291 R305 P307 H309 R20 L23 G27 L31 R92 L93 S96 D127 K130 Y132 K133 S135 Y137 W140 Q144 R158 P160 H162
BS02 dna AF R247 R251 R290 N315 I359 S371 F376 R100 R104 R143 N168 I212 S224 F229
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:7p5x, PDBe:7p5x, PDBj:7p5x
PDBsum7p5x
PubMed34851662
UniProtA0QW02

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