Structure of PDB 8jdj Chain AE

Receptor sequence

>8jdjAE (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]

IPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTK
RAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLD
NKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGV

3D structure

PDB

8jdj Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.

Chain

Resolution

2.5 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AE	V146 G147	V142 G143
BS02	rna	AE	K25 F28 K34 G35 V36 G37 R38 R39 Y40 W82 F83 N85 Q87 K88 D110 H120 R121 R124 H125 R130 V131 R132 Q134 H135 T136 K137 T138 R141 R142 G143 R144 T145	K21 F24 K30 G31 V32 G33 R34 R35 Y36 W78 F79 N81 Q83 K84 D106 H116 R117 R120 H121 R126 V127 R128 Q130 H131 T132 K133 T134 R137 R138 G139 R140 T141

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0014069	postsynaptic density
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0045202	synapse
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8jdj, PDBe:8jdj, PDBj:8jdj
PDBsum	8jdj
PubMed	37992713
UniProt	P62269\|RS18_HUMAN Small ribosomal subunit protein uS13 (Gene Name=RPS18)