Structure of PDB 5aj4 Chain AE

Receptor sequence

>5aj4AE (length=328) Species: 9823 (Sus scrofa) [Search protein sequence]

SFFTKLTADELWKGALAESRRKDLNRGQIIGEGRHGFLWPGLNIPLMRNG
AVQTIAQRSKEDQEKVEADMVQQREEWDRRRKMKVKRERGWSGNTWGGVS
LGPPDPGPNGETYDDFDTRILEVRNVFNMTAKEGRKRSVRVLVAVGNGKG
AAGFAIGKATERADAFRKAKNRAVHYLHYIERYEDHTIYHDISLKFKRTH
IKMKKQPRGYGLHCHRAIMTICRLIGIKDLYAKVSGSVNMLNLTRGLFLG
LSRQETHQQLADKKSLHVVEFREECGPLPIVVASPQGALRKDPEPEDEVP
DITLDWEDVKAAQGMKRSVWSGLKRAAT

3D structure

PDB

5aj4 The complete structure of the 55S mammalian mitochondrial ribosome.

Chain

Resolution

3.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	AE	T91 L93 L98 K100 G101 R136 S194 G195 N196 R226 V228 F229 N230 M231 T232 A233 K234 R237 R242 I258 K260 D266 R269 K270 H277 Y278 K299 R300 H315 C316 H317 R318 Y333 A334 K335 V336 S339 V340 R347 W408 R419 S420 V421 W422 S423 L425 R427	T4 L6 L11 K13 G14 R34 S92 G93 N94 R124 V126 F127 N128 M129 T130 A131 K132 R135 R140 I156 K158 D164 R167 K168 H175 Y176 K197 R198 H213 C214 H215 R216 Y231 A232 K233 V234 S237 V238 R245 W306 R317 S318 V319 W320 S321 L323 R325
BS02	rna	AE	F229 R237 R239	F127 R135 R137

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5aj4, PDBe:5aj4, PDBj:5aj4
PDBsum	5aj4
PubMed	25837512
UniProt	F1SU66

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