Structure of PDB 8ic5 Chain AC

Receptor sequence

>8ic5AC (length=373) Species: 10090 (Mus musculus) [Search protein sequence]

HPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTS
DTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSY
TFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIG
TTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNN
PTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYM
PANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFL
HTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASIS
YFSIILILMPISGIIEDKMLKLY

3D structure

PDB

8ic5 Respiratory complex CIII2, focus-refined of type I, PERK -/- mouse under cold temperature

Chain

Resolution

4.1 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEM	AC	Q44 I45 G48 L51 R80 H83 A87 A127 G130 P134 H182 F183 P186 F187	Q37 I38 G41 L44 R73 H76 A80 A120 G123 P127 H175 F176 P179 F180
BS02	HEM	AC	W31 G34 S35 L37 H97 R100 S106 W113 G116 L119 H196 L200 S205 N206	W24 G27 S28 L30 H90 R93 S99 W106 G109 L112 H189 L193 S198 N199
BS03	UQ6	AC	F18 L21 G38 L41 M42 L197 S205	F11 L14 G31 L34 M35 L190 S198

External links

PDB	RCSB:8ic5, PDBe:8ic5, PDBj:8ic5
PDBsum	8ic5
PubMed
UniProt	P00158\|CYB_MOUSE Cytochrome b (Gene Name=Mt-Cyb)

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