Structure of PDB 8iao Chain AC

Receptor sequence

>8iaoAC (length=373) Species: 10090 (Mus musculus) [Search protein sequence]

HPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTS
DTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSY
TFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIG
TTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNN
PTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYM
PANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFL
HTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASIS
YFSIILILMPISGIIEDKMLKLY

3D structure

PDB

8iao Respiratory complex CI:CIII2, type I, Wild type mouse under thermoneutral temperature

Chain

Resolution

4.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEM	AC	Q44 I45 G48 L51 A52 H83 G130 P134 H182 F183 P186 F187	Q37 I38 G41 L44 A45 H76 G123 P127 H175 F176 P179 F180
BS02	HEM	AC	W31 G34 L37 G38 L94 H97 R100 S106 G116 H196 S205 N206	W24 G27 L30 G31 L87 H90 R93 S99 G109 H189 S198 N199
BS03	U10	AC	F121 M124 F128 I146 P270 Y278 L294	F114 M117 F121 I139 P263 Y271 L287
BS04	UQ6	AC	S17 F18 L21 L197 F220	S10 F11 L14 L190 F213

External links

PDB	RCSB:8iao, PDBe:8iao, PDBj:8iao
PDBsum	8iao
PubMed
UniProt	P00158\|CYB_MOUSE Cytochrome b (Gene Name=Mt-Cyb)

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