Structure of PDB 6r6g Chain AB

Receptor sequence
>6r6gAB (length=403) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
ADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLR
ENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNV
IMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNAT
KARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFE
EMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGH
AKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMQFTLRD
MYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDS
MNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMV
KKM
3D structure
PDB6r6g Structural and mutational analysis of the ribosome-arresting human XBP1u.
ChainAB
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna AB T377 D380 S381 M382 N383 D384 Q399 G401 R402 R405 R408 G409 S410 G411 T346 D349 S350 M351 N352 D353 Q368 G370 R371 R374 R377 G378 S379 G380
BS02 peptide AB Q335 F336 I339 L349 F427 M430 M434 Q304 F305 I308 L318 F396 M399 M403
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6r6g, PDBe:6r6g, PDBj:6r6g
PDBsum6r6g
PubMed31246176
UniProtP61010|SRP54_CANLF Signal recognition particle subunit SRP54 (Gene Name=SRP54)

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