Structure of PDB 8qnz Chain AAA

Receptor sequence
>8qnzAAA (length=243) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
KEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTF
KIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPV
YQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISF
LRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWW
VGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP
3D structure
PDB8qnz Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem
ChainAAA
Resolution1.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8YF AAA A69 S70 I102 S118 T209 G210 Y211 L247 R250 A47 S48 I80 S96 T187 G188 Y189 L225 R228
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8qnz, PDBe:8qnz, PDBj:8qnz
PDBsum8qnz
PubMed38161376
UniProtQ6XEC0

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