Structure of PDB 8e52 Chain AAA

Receptor sequence
>8e52AAA (length=279) Species: 37998 (Parengyodontium album) [Search protein sequence]
AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFE
GRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNG
SGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQS
SGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLD
IFGPGTSILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACR
YIADTANKGDLSNIPFGTVNLLAYNNYQA
3D structure
PDB8e52 Electron-counting MicroED data with the K2 and K3 direct electron detectors.
ChainAAA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.64: peptidase K.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA AAA W113 R290 W8 R185
BS02 CA AAA H177 I325 M330 H72 I220 M225
BS03 CA AAA H174 H177 C178 H69 H72 C73
BS04 CA AAA D144 H174 C178 D39 H69 C73
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:8e52, PDBe:8e52, PDBj:8e52
PDBsum8e52
PubMed36044956
UniProtP06873|PRTK_PARAQ Proteinase K (Gene Name=PROK)

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