Structure of PDB 7zg2 Chain AAA

Receptor sequence

>7zg2AAA (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDA
VKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY
NKPGDDIVLMAEALEKLFLQKINELPTEE

3D structure

PDB

7zg2 Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Chain

AAA

Resolution

1.18 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	8WS	AAA	V87 L94 N140	V48 L55 N101

External links

PDB	RCSB:7zg2, PDBe:7zg2, PDBj:7zg2
PDBsum	7zg2
PubMed	36367089
UniProt	O60885\|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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