Structure of PDB 7zaj Chain AAA

Receptor sequence

>7zajAAA (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDA
VKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY
NKPGDDIVLMAEALEKLFLQKINELPTEE

3D structure

PDB

7zaj Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Chain

AAA

Resolution

1.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HH8	AAA	P82 V87 N140 I146	P43 V48 N101 I107
BS02	HH8	AAA	I146 M149	I107 M110

External links

PDB	RCSB:7zaj, PDBe:7zaj, PDBj:7zaj
PDBsum	7zaj
PubMed	36367089
UniProt	O60885\|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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