Structure of PDB 7za7 Chain AAA

Receptor sequence

>7za7AAA (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDA
VKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY
NKPGDDIVLMAEALEKLFLQKINELPTEE

3D structure

PDB

7za7 Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Chain

AAA

Resolution

1.06 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	IIS	AAA	M43 P95	M4 P56
BS02	IIS	AAA	W81 P82 Q85	W42 P43 Q46

External links

PDB	RCSB:7za7, PDBe:7za7, PDBj:7za7
PDBsum	7za7
PubMed	36367089
UniProt	O60885\|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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