Structure of PDB 7q52 Chain AAA

Receptor sequence
>7q52AAA (length=312) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
IDPLEALMTNPVVPESKRFCWNCGRPVGRGASEGWCPYCGSPYSFLPQLN
PGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQ
AMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKR
SKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLI
DLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDL
PTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQL
TGVLREVVAQDT
3D structure
PDB7q52 Cosolvent Sites-Based Discovery of Mycobacterium Tuberculosis Protein Kinase G Inhibitors.
ChainAAA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE AAA C34 C37 C56 C59 C20 C23 C36 C39
BS02 8ZC AAA I85 M160 E161 Y162 V163 M211 I220 I65 M140 E141 Y142 V143 M191 I200
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7q52, PDBe:7q52, PDBj:7q52
PDBsum7q52
PubMed35737472
UniProtP9WI73|PKNG_MYCTU Serine/threonine-protein kinase PknG (Gene Name=pknG)

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