Structure of PDB 7px5 Chain AAA

Receptor sequence
>7px5AAA (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
QEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMD
LSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACA
LRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB7px5 Exiting the tunnel of uncertainty: crystal soak to validated hit.
ChainAAA
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 12Q AAA V1008 V1013 N1064 I1074 V28 V33 N84 I94
External links
PDB RCSB:7px5, PDBe:7px5, PDBj:7px5
PDBsum7px5
PubMed36322414
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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