Structure of PDB 7plr Chain AAA

Receptor sequence
>7plrAAA (length=184) Species: 11577 (La Crosse virus) [Search protein sequence]
GMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEY
RNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSN
ESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELY
PTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVA
3D structure
PDB7plr Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound Baloxavir
ChainAAA
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 E4Z AAA M31 H34 D52 D79 D92 K94 M32 H35 D53 D80 D93 K95
BS02 MN AAA S44 I152 V153 S45 I153 V154
BS03 MN AAA H34 D79 D92 Y93 H35 D80 D93 Y94
BS04 MN AAA D52 D79 D53 D80
External links
PDB RCSB:7plr, PDBe:7plr, PDBj:7plr
PDBsum7plr
PubMed38656310
UniProtA5HC98|L_BUNLC RNA-directed RNA polymerase L (Gene Name=L)

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