Structure of PDB 7pgo Chain AAA

Receptor sequence
>7pgoAAA (length=244) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
GKEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPAST
FKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVP
VYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQIS
FLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGW
WVGWVELDDNVWFFAMNMDMPTSDGLGLAQAITKEVLKQEKIIP
3D structure
PDB7pgo Crystal Structure of a Class D Carbapenemase_R250A
ChainAAA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1BO AAA W47 T167 R174 W26 T146 R153
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7pgo, PDBe:7pgo, PDBj:7pgo
PDBsum7pgo
PubMed
UniProtQ6XEC0

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