Structure of PDB 7pdw Chain AAA

Receptor sequence

>7pdwAAA (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]

KEVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMSIY
SNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAVRGTGRRALTF
GSGTRLQVQPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDS
DVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS

3D structure

PDB

7pdw Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.

Chain

AAA

Resolution

1.82 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	AAA	R93 T95 G96 R98	R91 T93 G94 R96

External links

PDB	RCSB:7pdw, PDBe:7pdw, PDBj:7pdw
PDBsum	7pdw
PubMed	35851311

[Back to BioLiP]