Structure of PDB 7on0 Chain AAA

Receptor sequence

>7on0AAA (length=209) Species: 1577051 (Thermus sp. 2.9) [Search protein sequence]

MKRTYPEPTPIYHITHIDNLKGILRMGKLLAHNQSPPKQRSIAYAHIQER
RNRAKVPQPPGGVLHDYVPFYFCPRSPMLYAIYSGATEYQGGQEPILHLV
SSAQAVHKAGLPFVFTDRHGVLSHARFFRQLEELAQLDWEAIQASYWADP
PELREKKQAAFLVYKAFPWALIEEIAVYSQRVGEEVLKILKQFPEARRPR
VCIRKDWYY

3D structure

PDB

7on0 Molecular basis for DarT ADP-ribosylation of a DNA base.

Chain

AAA

Resolution

1.46 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.4.2.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	AAA	A43 Y44 H46 I47 R50 R75 P77 M78 Y80 A81 S84 A86 H119 S145 Y146 W147 A148 R154 Q158	A43 Y44 H46 I47 R50 R75 P77 M78 Y80 A81 S84 A86 H119 S145 Y146 W147 A148 R154 Q158
BS02	AR6	AAA	H13 T15 N19 G22 I23 M26 L29 L30 P36 P37 K38 A43 Y44 I47 Q48 R51 P69 M78	H13 T15 N19 G22 I23 M26 L29 L30 P36 P37 K38 A43 Y44 I47 Q48 R51 P69 M78

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0016757	glycosyltransferase activity
GO:0016779	nucleotidyltransferase activity

View graph for
Molecular Function

External links

PDB	RCSB:7on0, PDBe:7on0, PDBj:7on0
PDBsum	7on0
PubMed	34408320
UniProt	A0A0B0SG80\|DART_THES0 DNA ADP-ribosyl transferase (Gene Name=darT)

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