Structure of PDB 7oa4 Chain AAA

Receptor sequence
>7oa4AAA (length=184) Species: 11577 (La Crosse virus) [Search protein sequence]
GMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEY
RNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSN
ESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELY
PTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVA
3D structure
PDB7oa4 Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
ChainAAA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0N8 AAA L30 M31 H34 D52 H75 D79 K94 L31 M32 H35 D53 H76 D80 K95
BS02 MN AAA H34 D79 D92 Y93 H35 D80 D93 Y94
BS03 MN AAA D52 D79 D53 D80
External links
PDB RCSB:7oa4, PDBe:7oa4, PDBj:7oa4
PDBsum7oa4
PubMed38656310
UniProtA5HC98|L_BUNLC RNA-directed RNA polymerase L (Gene Name=L)

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