Structure of PDB 7ndu Chain AAA

Receptor sequence

>7nduAAA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQCAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP

3D structure

PDB

7ndu Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.

Chain

AAA

Resolution

2.9 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	AAA	Y7 H9 R62 E63 S66 T70 I73 N77 T80 Y84 W97 H99 E114 C116 S143 K146 H155 Q156 Y159 W167 Y171	Y7 H9 R62 E63 S66 T70 I73 N77 T80 Y84 W97 H99 E114 C116 S143 K146 H155 Q156 Y159 W167 Y171

External links

PDB	RCSB:7ndu, PDBe:7ndu, PDBj:7ndu
PDBsum	7ndu
PubMed	35108401
UniProt	P13747\|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

[Back to BioLiP]