Structure of PDB 7ndt Chain AAA

Receptor sequence
>7ndtAAA (length=271) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDGRFLRGYEQCAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGQDTELVETRPAGDGTFQKWAAVVVPSGEEQ
RYTCHVQHEGLPEPVTLRWKP
3D structure
PDB7ndt Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
ChainAAA
Resolution2.999 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide AAA Y7 H9 E63 S66 A67 I73 F74 N77 T80 Y84 L95 W97 H99 C116 W133 S143 E152 H155 Q156 Y159 W167 Y171 Y6 H8 E62 S65 A66 I72 F73 N76 T79 Y83 L94 W96 H98 C115 W132 S142 E151 H154 Q155 Y158 W166 Y170
External links
PDB RCSB:7ndt, PDBe:7ndt, PDBj:7ndt
PDBsum7ndt
PubMed35108401
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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