Structure of PDB 7ndq Chain AAA

Receptor sequence

>7ndqAAA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP

3D structure

PDB

7ndq Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.

Chain

AAA

Resolution

2.551 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	AAA	Y7 E63 S66 T70 I73 N77 T80 Y84 W97 E114 S143 K146 H155 Y159 W167 Y171	Y7 E63 S66 T70 I73 N77 T80 Y84 W97 E114 S143 K146 H155 Y159 W167 Y171

External links

PDB	RCSB:7ndq, PDBe:7ndq, PDBj:7ndq
PDBsum	7ndq
PubMed	35108401
UniProt	P13747\|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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