Structure of PDB 7a6x Chain AAA

Receptor sequence
>7a6xAAA (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
GEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSH
DRNEPFVFSLGKGQVIKAWDIGVATMKKGEIAHLLIKPEYAYGSAGSLPK
IPSNATLFFEIELLDFKG
3D structure
PDB7a6x Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors.
ChainAAA
Resolution1.67 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R3B AAA Y57 D68 G84 Q85 V86 I87 W90 Y113 K121 F130 Y36 D47 G63 Q64 V65 I66 W69 Y92 K100 F109
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:7a6x, PDBe:7a6x, PDBj:7a6x
PDBsum7a6x
PubMed33666419
UniProtQ13451|FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (Gene Name=FKBP5)

[Back to BioLiP]