Structure of PDB 6yq3 Chain AAA

Receptor sequence

>6yq3AAA (length=252) Species: 2093747 (Streptomyces sp. QL37) [Search protein sequence]

SRLTGKNALVTGSSRGIGRATAVRLAREGALVAVHYASNEAAADETVAQI
EREGGRAFPVRAELGVAGDVHELFLGLEQGLKERTGETTLDILVNNAAVT
DGILPEDVTAEQLDRYYAVNAKAPFLLVQRAVRNMPDGGRIINISSGLTR
CAVPEQVAYSMTKGALEQITLHMAKHLAPRGITVNSVAPGITDNGGAVFD
IPEIVEQMAQSSAFKRVGEAGDVADVVTFIATDESRWITGAFIDASGGTL
LG

3D structure

PDB

6yq3 Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.

Chain

AAA

Resolution

1.57 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	G17 S149 Y162
Catalytic site (residue number reindexed from 1)	G16 S146 Y159
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	AAA	G13 S15 R16 G17 I18 H36 A38 S39 N40 L65 N97 A98 A99 V122 I147 Y162 K166 P192 G193 I194 T195 N197	G12 S14 R15 G16 I17 H35 A37 S38 N39 L64 N96 A97 A98 V119 I144 Y159 K163 P189 G190 I191 T192 N194
BS02	P7Q	AAA	S149 G150 L151 Q159 Y162 I194 T252	S146 G147 L148 Q156 Y159 I191 T249

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:6yq3, PDBe:6yq3, PDBj:6yq3
PDBsum	6yq3
PubMed	32840360
UniProt	A0A2S6PN47

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