Structure of PDB 6yjv Chain AAA

Receptor sequence
>6yjvAAA (length=504) Species: 9606 (Homo sapiens) [Search protein sequence]
SLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLE
KRKRKKVLVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGH
DIRISASLAELKEIMGGGGVELIYIDIVGLAQFKKTLGPSWVHYQCMLRV
LDSFGTEPEFNHANYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGF
VVEQHLNINEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYTK
NIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFL
NPKFNPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQE
EVEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHVMWPPLSA
LQVKLAEPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSELA
KDILVPSFDPKNKHCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVALC
KDCL
3D structure
PDB6yjv Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
ChainAAA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.155: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN AAA P294 E297 F537 K541 P81 E84 F315 K319
BS02 U2F AAA G292 G293 P294 L295 G296 Y439 K441 P505 G508 P509 A510 E513 G79 G80 P81 L82 G83 Y220 K222 P283 G286 P287 A288 E291
Gene Ontology
Molecular Function
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
Biological Process
GO:0006487 protein N-linked glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6yjv, PDBe:6yjv, PDBj:6yjv
PDBsum6yjv
PubMed
UniProtQ09328|MGT5A_HUMAN Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Gene Name=MGAT5)

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