Structure of PDB 6yju Chain AAA

Receptor sequence
>6yjuAAA (length=502) Species: 9606 (Homo sapiens) [Search protein sequence]
SLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLE
KRKRKKVLVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGH
DIRISASLAELKEIMGGGGVELIYIDIVGLAQFKKTLGPSWVHYQCMLRV
LDSFGTEPEFNHANYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGF
VVEQHLNKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYTKNIPS
YVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNPKF
NPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNQEEVED
AVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHGQVMWPPLSALQ
VKLAEPGQSCKQVCQESQLICEPSFFQHLNKDKDMLKYKVTCQSSELAKD
ILVPSFDPKNKHCVFQGDLLLFSCAGAHPRHQRVCPCRDFIKGQVALCKD
CL
3D structure
PDB6yju Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
ChainAAA
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.155: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN AAA P294 E297 F537 K541 P81 E84 F311 K315
BS02 UDP AAA P294 L295 G296 Y439 K441 T465 L484 L489 G508 P509 A510 E513 P81 L82 G83 Y216 K218 T242 L258 L263 G282 P283 A284 E287
Gene Ontology
Molecular Function
GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
Biological Process
GO:0006487 protein N-linked glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6yju, PDBe:6yju, PDBj:6yju
PDBsum6yju
PubMed
UniProtQ09328|MGT5A_HUMAN Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Gene Name=MGAT5)

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