Structure of PDB 6tso Chain AAA

Receptor sequence

>6tsoAAA (length=292) Species: 181124 (Marasmius oreades)

SLRRGIYHIENAGVPSAIDLKDGSSSDGTPIVGWQFTPDTINWHQLWLAE
PIPNVADTFTLCNLFSGTYMDLYNGSSEAGTAVNGWQGTAFTTNPHQLWT
IKKSSDGTSYKIQNYGSKTFVDLVNGDSSDGAKIAGWTGTWDEGNPHQKW
YFNRMSVSSAEAQAAIARNPHIHGTYRGYILDGEYLVLPNATFTQIWKDS
GLPGSKWREQIYDCDDFAIAMKAAVGKWGADSWKANGFAIFCGVMLGVNK
AGDAAHAYNFTLTKDHADIVFFEPQNGGYLNDIGYDSYMAFY

3D structure

• PDB: 6tso Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti .
• Chain: AAA
• Resolution: 2.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GAL	AAA	D20 K22 D23 W35 H45	D19 K21 D22 W34 H44
BS02	GLA	AAA	W35 Q36 F37 T38 N43 Q46	W34 Q35 F36 T37 N42 Q45
BS03	GLA	AAA	D72 Y74 W87 N95 H97	D71 Y73 W86 N94 H96
BS04	GLA	AAA	W87 Q88 N95	W86 Q87 N94
BS05	GLA	AAA	D123 V125 N126 W138 N146 H148	D122 V124 N125 W137 N145 H147
BS06	GLA	AAA	W138 T139 E144 N146	W137 T138 E143 N145
BS07	CA	AAA	Q211 D214 D216 D217	Q210 D213 D215 D216
BS08	CA	AAA	D214 D216	D213 D215
BS09	CD	AAA	C215 H257	C214 H256
BS10	CD	AAA	H172 D287	H171 D286

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding

External links

• PDB: RCSB:6tso, PDBe:6tso, PDBj:6tso
• PDBsum: 6tso
• PubMed: 34235469
• UniProt: Q8X123