Structure of PDB 6tix Chain AAA

Receptor sequence
>6tixAAA (length=498) Species: 632 (Yersinia pestis) [Search protein sequence]
VPIAPSRGMIFDRNGTPLALNRTIYQLELSATLNALRPIVDLTDDDIANF
EIAVKTPLTEVQVARFAVNQFRFPGIEVKGYQRRFYPYGSALTHVIGYVS
KINDKDVERLDKEGILPNYAATHDIGKLGIERYYESTLHGKTGYEEQPPQ
AGKDIYLTLDLSLQIYIEKLLSGSRAAVVVTDPRTGGILALVSNPSYDPN
LFVDGISNKDYQGLLNDTNRPLINRATQGVYPPASTVKPYIAVSALSAGV
ITKNTSLFDPGWWQLPKRYRDWKKWGHGRLNVTKALEESADTFFYQVAYD
MGIDRLSSWMSKFGYGEYTGIDLSEERAGLMPTREWKQKRHKKPWYQGDT
IPVGIGQGYWTATPIQMAKSLMTLINDGTVKTPHLLQSTRIDGVLVPYKQ
EDSTQIGSINSGYWEIAKDGMYGVANRPNGTGRKFFEGTPYKAAAKSGTA
QRDHKLMVAFAPYENPTVSVAIILENGGAGPAVGTITRQILDHILLGD
3D structure
PDB6tix The structure of penicillin-binding protein 2 from Yersinia pestis in complex with mecillinam
ChainAAA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DH4 AAA A330 S331 K334 W371 S388 D390 S546 G547 T548 A234 S235 K238 W272 S289 D291 S447 G448 T449
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008658 penicillin binding
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tix, PDBe:6tix, PDBj:6tix
PDBsum6tix
PubMed
UniProtA0A0H2W2Y2

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