Structure of PDB 8ove Chain A7

Receptor sequence
>8oveA7 (length=303) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
AVAYEGQLTGHRGWVTSLACPQTTTKVVSTSRDKTLLSWGPNPDRHSSEC
SYGLPDRRLEGHSAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYK
FLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKCMHTLSRGAHTDWVS
CVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSP
DGSLCASSDKDGVARLWDLTKGEALSEMAAGAPINQICFSPNRYWMCAAT
EKGIRIFDLENKDIIVELAPESIVPECVSIAWSADGSTLYSGYTDNVIRV
WGV
3D structure
PDB8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
ChainA7
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A7 R13 S67 R12 S63
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0005080 protein kinase C binding
GO:0043022 ribosome binding
GO:0045182 translation regulator activity
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0006417 regulation of translation
GO:0006915 apoptotic process
GO:0032465 regulation of cytokinesis
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum8ove
PubMed37985661
UniProtP69103|GBLP_TRYBB Small ribosomal subunit protein RACK1

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