Structure of PDB 5m1j Chain A6

Receptor sequence
>5m1jA6 (length=539) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
DMPDFHDEGEFDDYLNDDEYDLMNEVFPTLKAQLQDYQGWDNLSLKLALF
DNNFDLESTLAELKKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVV
LGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQ
TNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMA
ILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQ
QRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWY
NGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVS
GKLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQGQSTNHEETDVAIKGD
FVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPG
TPFILFIGVKEQPARIKRLISFIDKGNTASKKKIRHLGSKQRAFVEIELI
EVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ
3D structure
PDB5m1j Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
ChainA6
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A6 D177 K211 S213 H255 R256 S285 L289 D290 D105 K139 S141 H183 R184 S213 L217 D218
BS02 GNP A6 V176 G179 K180 S181 T182 F214 V231 K314 N317 S352 G353 F354 V104 G107 K108 S109 T110 F142 V159 K242 N245 S280 G281 F282
BS03 MG A6 H306 R588 H234 R516
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0006417 regulation of translation
GO:0032790 ribosome disassembly
GO:0045727 positive regulation of translation
GO:0045948 positive regulation of translational initiation
GO:0070651 nonfunctional rRNA decay
GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990533 Dom34-Hbs1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5m1j, PDBe:5m1j, PDBj:5m1j
PDBsum5m1j
PubMed27995908
UniProtP32769|HBS1_YEAST Elongation factor 1 alpha-like protein (Gene Name=HBS1)

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