Structure of PDB 8tpu Chain A3

Receptor sequence

>8tpuA3 (length=119) Species: 36329 (Plasmodium falciparum 3D7)

NVKAYELRTLKKKELLDKLDELKKELSGLRISKALGNSAKNSKIHGVRKN
VARVLTVYNQKRKMELRQLYKNKKFKPYNLRKKLTKNKRLQLSPKQKAAM
TLRQKKKVQNFPQRKYLVV

3D structure

• PDB: 8tpu Divergent translational landscape reflects adaptation to biased codon usage in malaria parasites
• Chain: A3
• Resolution: 4.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A3	R69 K73 F77 Y80 K84 K88 K97 R105 K108 N112	R67 K71 F75 Y78 K82 K86 K95 R103 K106 N110
BS02	rna	A3	A6 R10 K14 K35 N43 R50 A54 R55 L57 T58 Y60 N61 Q62 R64 K65 Y80 K84 K85 T87 K88 R91	A4 R8 K12 K33 N41 R48 A52 R53 L55 T56 Y58 N59 Q60 R62 K63 Y78 K82 K83 T85 K86 R89

External links

• PDB: RCSB:8tpu, PDBe:8tpu, PDBj:8tpu
• PDBsum: 8tpu
• UniProt: Q8IIB4