Structure of PDB 4v8a Chain A3

Receptor sequence
>4v8aA3 (length=59) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA
HLVRVEVVE
3D structure
PDB4v8a The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
ChainA3
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A3 K10 S11 I13 G14 P16 K17 K20 A21 A22 K24 A25 R29 R30 L31 Q32 P41 A42 N46 K49 K9 S10 I12 G13 P15 K16 K19 A20 A21 K23 A24 R28 R29 L30 Q31 P40 A41 N45 K48
BS02 rna A3 Y15 Q19 H52 Y14 Q18 H51
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:4v8a, PDBe:4v8a, PDBj:4v8a
PDBsum4v8a
PubMed22240456
UniProtQ5SHQ6|RL30_THET8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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