Structure of PDB 8aph Chain A1

Receptor sequence
>8aphA1 (length=523) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
FFKTTEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIQIQVSPTTFAAGLV
FNLEKDGRIGIILMDNITEVQSGQKVMATGQLLHIPVGAGVLGKVVNPLG
HEVPVGTLGKVDTGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIV
GDRQTGKTSIAVSTIINQVRINQQILSKNAVISIYVSIGQRCSNVARIHR
LLQSYGALRYTTVMAATAAEPAGLQYLAPYAGVTMGEYFMNRGRHCLCVY
DDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGG
GSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIG
LSVSRVGSSAQNAAMKGVAGKLKGILAEYRKLAADVQTIPMIRGARFVAL
FNQKQPSYFMNAIVSLYACLNGYLDDVKVQYVKFYEYLLVHRDLGIMYGT
AKNKFFYMYVQELNYLIRFFTLNSPILHGELEEMLKQHTHLFLQHYQSKM
NAIKSEKDVKALKNLLYSCKRAV
3D structure
PDB8aph An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
ChainA1
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A1 R208 Q209 G211 K212 T213 S214 R399 K465 R153 Q154 G156 K157 T158 S159 R344 K404
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Cellular Component
External links
PDB RCSB:8aph, PDBe:8aph, PDBj:8aph
PDBsum8aph
PubMed36220811
UniProtQ9GS23|ATPA_TRYBB ATP synthase subunit alpha, mitochondrial (Gene Name=Tb427.07.7420)

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