Structure of PDB 8ova Chain A0

Receptor sequence
>8ovaA0 (length=220) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
EAMSRKEWYDVVAPKNFEVRQFAKTICNKTQGTKIAADFLRGRVYEGNLA
DLNKNEDDAYRKVKFTVQEVQGRNLLTQFHGMDMTSDRVYYLLRKWCTTI
EATVEAKTADGYGLRLFLIAFTKKQENQLSKNCYAKTRLVKWVRMRATNI
IRRRLAKLDINDAVSLLTRNILRDRLAKRCNPIIPLRDLRIRKVKVIRTP
KFDAQALIAAHGEVPTSAEG
3D structure
PDB8ova A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
ChainA0
Resolution2.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A0 R26 L116 K118 W119 R138 F140 Q148 N150 Q151 S153 K154 N155 Y157 T160 W165 R167 M168 R169 N204 P205 I206 K218 R5 L93 K95 W96 R115 F117 Q125 N127 Q128 S130 K131 N132 Y134 T137 W142 R144 M145 R146 N181 P182 I183 K195
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ova, PDBe:8ova, PDBj:8ova
PDBsum8ova
PubMed37985661
UniProtQ38BK6

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