Structure of PDB 9ima Chain A

Receptor sequence
>9imaA (length=249) Species: 9606 (Homo sapiens) [Search protein sequence]
GPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVLPTQLLFLLS
VLGLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVR
GCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRGMMFVNMTPCQLNVD
FVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVV
WISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRS
3D structure
PDB9ima Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma.
ChainA
Resolution2.65 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A I142 T149 R154 I123 T130 R135
BS02 CLR A G135 L139 G116 L120
BS03 CLR A I143 D169 V172 I124 D150 V153
External links
PDB RCSB:9ima, PDBe:9ima, PDBj:9ima
PDBsum9ima
PubMed39181182
UniProtQ9NZD1|GPC5D_HUMAN G-protein coupled receptor family C group 5 member D (Gene Name=GPRC5D)

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