Structure of PDB 9ftw Chain A

Receptor sequence
>9ftwA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
DAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPK
PLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLRE
IMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGF
EHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPDVLA
MQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLA
VRTYTWDKSTYGNGKKYIATAYIVS
3D structure
PDB9ftw Molecular Basis for the Calcium-Dependent Activation of the Ribonuclease EndoU.
ChainA
Resolution1.65 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A Q210 E217 D279 E284 Q77 E84 D146 E151
BS02 CA A N204 N207 N208 E226 N71 N74 N75 E93
BS03 CA A D179 C181 D315 Y316 D46 C48 D182 Y183
BS04 CA A A135 E140 Q250 A2 E7 Q117
BS05 CA A D322 G323 W325 D330 D189 G190 W192 D197
External links
PDB RCSB:9ftw, PDBe:9ftw, PDBj:9ftw
PDBsum9ftw
PubMed39070628
UniProtP21128|ENDOU_HUMAN Uridylate-specific endoribonuclease (Gene Name=ENDOU)

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