Structure of PDB 9flo Chain A

Receptor sequence
>9floA (length=332) Species: 9606 (Homo sapiens) [Search protein sequence]
ECSQKGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAI
EGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCV
QGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQM
RTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKL
HYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDG
DYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTP
AMKQIKRKIQEFHRTMLNFSSATDLLCQHSLF
3D structure
PDB9flo Crystal structure of human Haspin (GSG2) kinase bound to MU2181
ChainA
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1IDC A I490 V498 A509 F605 F607 G608 L656 I686 D687 Y688 I25 V33 A44 F140 F142 G143 L191 I221 D222 Y223
External links
PDB RCSB:9flo, PDBe:9flo, PDBj:9flo
PDBsum9flo
PubMed
UniProtQ8TF76|HASP_HUMAN Serine/threonine-protein kinase haspin (Gene Name=HASPIN)

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