Structure of PDB 9fhd Chain A

Receptor sequence
>9fhdA (length=298) Species: 9606 (Homo sapiens) [Search protein sequence]
PRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVL
SLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCI
INNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKML
QRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG
FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRV
VDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
3D structure
PDB9fhd Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability.
ChainA
Resolution1.845 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1ICK A A224 A226 E227 P246 V250 T253 G257 C289 A224 A226 E227 P246 V250 T253 G257 C289
External links
PDB RCSB:9fhd, PDBe:9fhd, PDBj:9fhd
PDBsum9fhd
PubMed39179180
UniProtP50053|KHK_HUMAN Ketohexokinase (Gene Name=KHK)

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