Structure of PDB 9f9l Chain A

Receptor sequence
>9f9lA (length=194) Species: 9606 (Homo sapiens) [Search protein sequence]
PLELRPGEYRVLLCVDIGETRGRPELLRELQRLHVTHTVRKLHVGDFVWV
AQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGL
ERRVYLVEELSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTR
GLQRLYQGHTLRSRPWGTPGNPESGAMTSPNPLCSLLTFSDFNA
3D structure
PDB9f9l Fragment-Based Discovery of Novel MUS81 Inhibitors.
ChainA
Resolution2.02 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A D307 E333 R334 D46 E72 R73
BS02 A1IA8 A D307 E333 K335 R348 E351 Q352 R355 D46 E72 K74 R87 E90 Q91 R94
External links
PDB RCSB:9f9l, PDBe:9f9l, PDBj:9f9l
PDBsum9f9l
PubMed39015284
UniProtQ96NY9|MUS81_HUMAN Crossover junction endonuclease MUS81 (Gene Name=MUS81)

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