Structure of PDB 9f99 Chain A

Receptor sequence
>9f99A (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
PLELRPGEYRVLLCVDIGETRGGGHRPELLRELQRLHVTHTVRKLHVGDF
VWVAQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKR
CGLERRVYLVEELSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLAL
LTRGLQRLYQGHTLRSRPWGPNPLCSLLTFSDFNA
3D structure
PDB9f99 Fragment-Based Discovery of Novel MUS81 Inhibitors.
ChainA
Resolution2.803 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1IA5 A D307 E333 K335 S343 D49 E75 K77 S85
BS02 MG A G306 D307 G48 D49
BS03 MG A D307 E333 R334 D49 E75 R76
External links
PDB RCSB:9f99, PDBe:9f99, PDBj:9f99
PDBsum9f99
PubMed39015284
UniProtQ96NY9|MUS81_HUMAN Crossover junction endonuclease MUS81 (Gene Name=MUS81)

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