Structure of PDB 9f7x Chain A

Receptor sequence
>9f7xA (length=265) Species: 9606 (Homo sapiens) [Search protein sequence]
PESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSL
MMGEDKIKFLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLD
LNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF
GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ
DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTE
TDMSLHPLLQEIYKD
3D structure
PDB9f7x Structural Studies on the Binding Mode of Bisphenols to PPAR gamma.
ChainA
Resolution1.63 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K301 L311 N312 Q314 V315 L318 P467 L468 E471 K91 L101 N102 Q104 V105 L108 P257 L258 E261
BS02 H3W A I281 G284 C285 R288 S289 V339 I341 I71 G74 C75 R78 S79 V129 I131
External links
PDB RCSB:9f7x, PDBe:9f7x, PDBj:9f7x
PDBsum9f7x
PubMed38927044
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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