Structure of PDB 9f1m Chain A

Receptor sequence
>9f1mA (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPT
3D structure
PDB9f1m First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45
ChainA
Resolution1.90001 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H80 A W81 P82 V87 K91 L92 N140 D145 I146 M149 W39 P40 V45 K49 L50 N98 D103 I104 M107
External links
PDB RCSB:9f1m, PDBe:9f1m, PDBj:9f1m
PDBsum9f1m
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

[Back to BioLiP]